Catalog #CP156
RecombiMAb mouse IgG2a (LALA-PG) isotype control, unknown specificity
Clone
MOPC-21-CP156
Isotype
Mouse IgG2a, κ
Product Description
The MOPC-21-CP156 monoclonal antibody is a recombinant version of the original MOPC-21 antibody. The variable domain sequences are identical to the original MOPC-21 antibody but the constant region sequences have been switched from mouse IgG1 to mouse IgG2a. The LALA-PG substitution has been shown to decrease effector functions by disrupting the Fc/Fcγ receptor interface. The MOPC-21-CP156 monoclonal antibody is ideal for use as a non-reactive isotype-matched control for mouse IgG2a antibodies with a LALA-PG mutation in in vivo and in vitro applications.
Specifications
Isotype | Mouse IgG2a, κ |
---|---|
Recommended Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer |
Conjugation | This product is unconjugated. Conjugation is available via our Antibody Conjugation Services. |
Mutations | LALA-PG |
Formulation |
PBS, pH 7.0 Contains no stabilizers or preservatives |
Endotoxin |
≤0.5EU/mg (≤0.0005EU/μg) Determined by LAL gel clotting assay |
Purity |
≥95% Determined by SDS-PAGE |
Sterility | 0.2 µm filtration |
Production | Purified from CHO cell supernatant in an animal-free facility |
Purification | Protein G |
Molecular Weight | 150 kDa |
Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
Need a Custom Formulation? | See All Antibody Customization Options |