RecombiMAb mouse IgG2a (LALA-PG) isotype control, unknown specificity
Catalog #CP156
Clone:
MOPC-21-CP156
Isotype:
Mouse IgG2a
(switched from mouse IgG1)
(switched from mouse IgG1)
Product Details
The MOPC-21-CP156 monoclonal antibody is a recombinant version of the original MOPC-21 antibody. The variable domain sequences are identical to the original MOPC-21 antibody but the constant region sequences have been switched from mouse IgG1 to mouse IgG2a. The LALA-PG substitution has been shown to decrease effector functions by disrupting the Fc/FcĪ³ receptor interface. The MOPC-21-CP156 monoclonal antibody is ideal for use as a non-reactive isotype-matched control for mouse IgG2a antibodies with a LALA-PG mutation in in vivo and in vitro applications.Specifications
| Isotype | Mouse IgG2a, Īŗ |
|---|---|
| Recommended Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer |
| Mutations | LALA-PG |
| Formulation |
PBS, pH 7.0 Contains no stabilizers or preservatives |
| Endotoxin |
<1EU/mg (<0.001EU/Ī¼g) Determined by LAL gel clotting assay |
| Purity |
>95% Determined by SDS-PAGE |
| Sterility | 0.2 Āµm filtration |
| Production | Purified from CHO cell supernatant in an animal free facility |
| Purification | Protein G |
| Molecular Weight | 150 kDa |
| Murine Pathogen Tests |
Ectromelia/Mousepox Virus: Negative Hantavirus: Negative K Virus: Negative Lactate Dehydrogenase-Elevating Virus: Negative Lymphocytic Choriomeningitis virus: Negative Mouse Adenovirus: Negative Mouse Cytomegalovirus: Negative Mouse Hepatitis Virus: Negative Mouse Minute Virus: Negative Mouse Norovirus: Negative Mouse Parvovirus: Negative Mouse Rotavirus: Negative Mycoplasma Pulmonis: Negative Pneumonia Virus of Mice: Negative Polyoma Virus: Negative Reovirus Screen: Negative Sendai Virus: Negative Theilerās Murine Encephalomyelitis: Negative |
| Storage | The antibody solution should be stored at the stock concentration at 4Ā°C. Do not freeze. |
Additional Formats
Recommended Products
-
Recommended Dilution Buffer
InVivoPure pH 7.0 Dilution Buffer
