Antibody Production Services

At Bio X Cell, we recognize the technical challenges and time demands of growing hybridoma cells and purifying antibodies in large quantities with low endotoxin levels. Our experienced team is here to manage this for you. Utilizing our optimized fermentation process, we produce antibodies more efficiently than traditional methods. A dedicated technical project manager will guide you through every step, offering recommendations and updates. Our Antibody Production Services are based in the U.S., ensuring streamlined communication, rapid turnaround time, and quality.

Contact us to Discuss Your Project

Our Services Include:

We know that research moves at a fast and precise pace, and we aim to partner with you to achieve your goals. Our platform is customizable, allowing you to collaborate with our team to select à la carte services that improve the rigor of your experimental design. If you do not see a service listed, contact us at contractservices@bioxcell.com to provide more details about your project.

Request Contract Production Quote

Project Workflow

Phase
1. Pilot Instructions for preparing and shipping cells.
Assessment of cell line activity utilizing a small scale cell culture followed by either protein A or G affinity purification.
Mycoplasma testing service.
Antibody isotyping service.
2. Fermentation Cell culturing and monitoring 7 days/week.
Freezing of five vials of cells.
Storage of cells at Bio X Cell for rapid re-supply.
Expansion of cells using optimized fermentation process.
3. Purification Purification of supernatant on Protein A or G.
Buffer exchange to PBS that is preservative and stabilizer-free.
Sterile filtering of final product.
  • Testing to confirm <2EU/mg endotoxin.
  • <1EU/mg endotoxin level is available for an added charge.
4. Vialing and QC
  • Sterile vialing of finished product.
  • Custom aliquoting available.
Internal antibody quality assessment.
Certificate of Analysis.
Murine pathogen screening service.
5. Shipping Shipping on cold packs in environmentally friendly packaging.
Request Contract Production Quote
james@2x

"I am totally satisfied with the service Bio X Cell has given us. When anyone asks me for CTLA-4 antibodies, I always refer them to you. I look forward to another 20 years."

- James P. Allison

Co-Recipient of the 2018 Nobel Prize in Physiology or Medicine

Customer Testimonials

"Very reliable antibodies! Especially for functional experiments."

- Amit Singh

NIH

"I used lots of in vivo depletion antibodies from bioxcell. Their products and service are fantastic"

- Jintao Xu

University of Michgan

"Excellent, it works very well."

- Piu Saha

University of Toledo

"Good service"

- Smrithi S Menoon

The University of Toledo

"Our lab has been using Bio X Cell exclusively for the last few years and have a wonderful experience working with the company!"

- Ahmed Abokor

University of Toledo

"Very reliable antibodies! Especially for functional experiments."

- Amit Singh

NIH

"I used lots of in vivo depletion antibodies from bioxcell. Their products and service are fantastic"

- Jintao Xu

University of Michgan

"Excellent, it works very well."

- Piu Saha

University of Toledo

"Good service"

- Smrithi S Menoon

The University of Toledo

"Our lab has been using Bio X Cell exclusively for the last few years and have a wonderful experience working with the company!"

- Ahmed Abokor

University of Toledo