Catalog #CP148
RecombiMAb human IgG4 S228P L235E P329G (SPLEPG) isotype control, anti-hen egg lysozyme
Isotype
Human IgG4
Product Description
This human IgG4 isotype control antibody reacts with hen egg lysozyme and has low or no specific binding to any human sample. The S228P substitution is included to prevent Fab-arm exchange. The P329G substitution combined with S228P and L235E substitutions has been shown to decrease effector functions by disrupting the Fc/Fcγ receptor interface.
Specifications
| Isotype | Human IgG4 |
|---|---|
| Recommended Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer |
| Conjugation | This product is unconjugated. Conjugation is available via our Antibody Conjugation Services. |
| Mutations | S228P, L235E, P329G (SPLEPG) |
| Immunogen | Hen egg lysozyme (HEL) |
| Formulation |
PBS, pH 7.0 Contains no stabilizers or preservatives |
| Endotoxin |
≤0.5EU/mg (≤0.0005EU/μg) Determined by LAL gel clotting assay |
| Purity |
≥95% Determined by SDS-PAGE |
| Sterility | 0.2 µm filtration |
| Production | Purified from CHO cell supernatant in an animal-free facility |
| Purification | Protein A |
| RRID | AB_2927522 |
| Molecular Weight | 150 kDa |
| Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
| Need a Custom Formulation? | See All Antibody Customization Options |