Catalog #SIM0045

InVivoSIM anti-human CD326 (EpCAM) (Edrecolomab Biosimilar)

Clone Edrecolomab
Reactivities Human
Isotype Mouse IgG2a, κ

$235.00 - $8,140.00

$235.00 - $8.00

Choose an Option...
  • 100 mg - $8,140.00
  • 50 mg - $4,574.00
  • 25 mg - $3,182.00
  • 5 mg - $911.00
  • 1 mg - $235.00
  • Custom Amount (Quotes Only)
In stock
Only %1 left

Product Description

This biosimilar antibody uses the same variable regions as the therapeutic antibody Edrecolomab, making it ideal for research use. Edrecolomab is a murine monoclonal antibody which reacts with tumor-associated epithelial cell adhesion molecule (EpCAM), also known as CD326 and 17-1A. EpCAM is a 40-42 kDa cell-surface type 1 transmembrane glycoprotein expressed on most epithelial cells as well as a small subset of peripheral T cells, keratinocytes, Langerhans cells and thymic, lymph node, and splenic dendritic cells. EpCAM is also expressed by various carcinomas, including those of the colon and breast. CD326 mediates cell-cell adhesion and may function as a growth factor receptor. Upon binding to EpCAM, Edrecolomab recruits the body's immune effector cells, which may exhibit antitumor cytotoxicity.

Specifications

Isotype Mouse IgG2a, κ
Recommended Isotype Control(s) InVivoPlus mouse IgG2a isotype control, unknown specificity
Recommended Dilution Buffer InVivoPure pH 7.0 Dilution Buffer
Immunogen Human CD326
Reported Applications Functional assays
ELISA
Flow cytometry
Formulation PBS, pH 7.0
Contains no stabilizers or preservatives
Endotoxin ≤0.5EU/mg (≤0.0005EU/μg)
Determined by LAL gel clotting assay
Purity ≥95%
Determined by SDS-PAGE
Sterility 0.2 µm filtration
Production Purified from cell culture supernatant in an animal-free facility
Molecular Weight 150 kDa
Storage The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
Need a Custom Formulation? See All Antibody Customization Options

Product FAQs

Related Products

  1. Catalog #BE0346
    InVivoMAb anti-mouse CD326 (EpCAM) Read more
  2. Catalog #BE0386
    InVivoMAb anti-human CD326 (EpCAM) Read more
  3. Catalog #FM0346-APC
    FlowMAb APC anti-mouse CD326 (EpCAM) Read more
  4. Catalog #FM0346-FITC
    FlowMAb FITC anti-mouse CD326 (EpCAM) Read more
  5. Catalog #FM0346-PE
    FlowMAb PE anti-mouse CD326 (EpCAM) Read more