Beyond the Dish: Unlocking Tumor Microenvironment Biology with 3D Tissue Models and Antibody-Based Strategies

Register to watch the webinar on-demand here.

Summary:

Standard 3D models capture tumor microenvironment architecture, but they often miss the signals that matter most.

Watch our webinar to see how advanced 3D microtumor platforms and ML-driven screening expose tumor microenvironment (TME) vulnerabilities that conventional approaches routinely overlook.

You'll walk away with:

  • How a 3D microtumor screen uncovered a p38-dependent tumor–CAF–ECM circuit that standard assays missed entirely
  • A noncanonical DDR1/2–p38–GLI1 axis in CAFs and why it's a viable antibody target
  • Data showing kinase inhibition + anti-PD-L1 drives CD8⁺ T cell infiltration
  • A practical framework for selecting research-grade antibodies for organoid workflows

If you work with organoids, 3D tumor models, or antibody tools to study tumor microenvironment (TME) signaling, this one's for you.

Speakers:

Dr. Nao Nishida-Aoki
Waseda University

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