Bio X Cell In Print

Prophylactic treatment with antagonistic anti-TNFĪ± antibodies may improve outcomes of anti-PD-1 and anti-CTLA-4 combination cancer immunotherapy

The combination of anti-PD-1 and anti-CTLA-4 antibody-mediated immunotherapy is remarkably effective against melanoma, renal cell carcinoma, and non-small-cell lung cancer. However, this comes at the cost of frequent, serious immune-related adverse events. Colitis is among the most frequent and problematic of the immune-mediated adverse events that are associated with dual checkpoint inhibition.

Bio X Cellā€™sĀ anti-mouse PD-1 (clone RMP1-14), anti-mouse CTLA-4 (clone 9D9) and anti-mouse TNFĪ± (clone XT3.11) antibodies are used in these preclinical mouse models.

We Broke Ground

On May 28th Bio X Cell owner, Dr. Klaus Lubbe, gave a wonderful speech thanking Bio X Cell employees and all of the engineers, architects, city planners and contractors who have helped to make this vision a reality. Click here to view pictures and updates on Bio X Cell's new space!

 

BioResearch Product Faireā„¢

On Friday, June 28th from 10am-2:30pm Bio X Cell will be exhibiting atĀ The University of PittsburghĀ for theĀ BioResearch Product Faireā„¢. This is an excellent opportunity forĀ Graduate Students, Post Doctoral Candidates, Professors, Research Scientists, Grant Holders, Principal Investigators, Lab Managers orĀ University Purchasing Agents to learn about Bio X Cell's unmatched antibodies! ThisĀ event is fully catered and FREE for University of Pittsburgh life science research professionals to attend.

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