Catalog #SIM0032

InVivoSIM anti-human amyloid-beta (Lecanemab Biosimilar)

Clone Lecanemab
Reactivities Human
Isotype Human IgG1, κ

$235.00 - $8,140.00

$235.00 - $8.00

Choose an Option...
  • 100 mg - $8,140.00
  • 50 mg - $4,574.00
  • 25 mg - $3,182.00
  • 5 mg - $911.00
  • 1 mg - $235.00
  • Custom Amount (Quotes Only)
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Product Description

This non-therapeutic biosimilar antibody uses the same variable regions from the therapeutic antibody Lecanemab making it ideal for research use. This Lecanemab biosimilar is a recombinant humanized IgG1 antibody directed against aggregated soluble and insoluble forms of amyloid-beta (Aβ), which are implicated in the pathophysiology of Alzheimer’s disease. Lecanemab works to reduce Aβ plaques and prevent Aβ deposition in the brain with high selectivity to Aβ protofibrils.

Specifications

Isotype Human IgG1, κ
Recommended Isotype Control(s) RecombiMAb human IgG1 isotype control, anti-hen egg lysozyme
Recommended Dilution Buffer InVivoPure pH 7.0 Dilution Buffer
Conjugation This product is unconjugated. Conjugation is available via our Antibody Conjugation Services.
Immunogen Human amyloid-beta
Reported Applications Functional assays
Formulation PBS, pH 7.0
Contains no stabilizers or preservatives
Endotoxin ≤0.5EU/mg (≤0.0005EU/μg)
Determined by LAL gel clotting assay
Purity ≥95%
Determined by SDS-PAGE
Sterility 0.2 µm filtration
Production Purified from cell culture supernatant in an animal-free facility
Purification Protein A
Molecular Weight 150 kDa
Storage The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
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