InVivoMAb recombinant Flt-3L-Ig (hum/hum)
Product Details
Flt-3L (FMS-related Tyrosine Kinase 3 Ligand) is an endogenous protein that functions as a cytokine and growth factor. Flt-3L is crucial for the development of conventional dendritic cells (cDCs) and plasmacytoid dendritic cells (pDCs). Recombinant Flt-3L-Ig is a fusion protein consisting of human Flt-3L fused to the Fc portion of human IgG1. This fusion protein is useful for activating Flt3 signaling and inducing the expansion of DC populations. Human Flt-3L-Ig is frequently reported to stimulate Flt3 signaling in vivo in mice.Specifications
Recommended Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer |
---|---|
Conjugation | This product is unconjugated. Conjugation is available via our Antibody Conjugation Services. |
Formulation |
PBS, pH 7.0 Contains no stabilizers or preservatives |
Endotoxin |
<2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay |
Purity |
>95% Determined by SDS-PAGE |
Sterility | 0.2 µm filtration |
Production | Purified from cell culture supernatant in an animal-free facility |
Purification | Protein A |
RRID | BE0342 |
Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
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Preprint on BioRxiv : the Preprint Server for Biology on 21 September 2024 by Lobel, G. P., Han, N., et al.
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