Catalog #RP056
Recombinant human/mouse FGF-9 protein
Reactivities
Porcine, Mouse, Human, Rat, Bovine
Applications
Chemically defined media
Kidney organoid generation
Kidney organoid generation
Product Description
Recombinant human/mouse FGF-9 protein (fibroblast growth factor 9), also known as glia-activating factor, is a member of the fibroblast growth factor (FGF) family that binds and activates the 'c' splice isoforms of FGF receptors 1–3 and can activate ERK, STAT, PI3K and MAP kinase signaling pathways. FGF-9 is implicated in many developmental processes, including lung and skeletal development, sex determination and neural patterning in the optic neuroepithelium, and it modulates the development and survival of neurons and glia. FGF-9 has also been reported to play pro-survival roles, enhancing cell proliferation and alleviating cell death, in neurodegenerative diseases such as Parkinson's disease, Huntington's disease and Alzheimer's disease. In cell culture, FGF-9 is commonly used in the generation of kidney organoids, making recombinant FGF-9 a key reagent for organoid, developmental biology and neuroscience research.
This protein is optimized for in vivo and functional applications: low-endotoxin, tag-free, and carrier-free, supporting reproducible performance in demanding preclinical and bioactivity studies.
A GMP-grade version of this protein is available for cell and gene therapy manufacturing. Contact us at customerservice@bioxcell.com for details.
Species reactivity: human. Species similarity: mouse - 99%, rat - 99%, bovine - 98%, porcine - 98%.
This protein is optimized for in vivo and functional applications: low-endotoxin, tag-free, and carrier-free, supporting reproducible performance in demanding preclinical and bioactivity studies.
A GMP-grade version of this protein is available for cell and gene therapy manufacturing. Contact us at customerservice@bioxcell.com for details.
Species reactivity: human. Species similarity: mouse - 99%, rat - 99%, bovine - 98%, porcine - 98%.
Specifications
| Reported Applications |
Chemically defined media Kidney organoid generation |
|---|---|
| Formulation | Lyophilized, white powder |
| Purity |
≥95% Determined by SDS-PAGE |
| Sterility | Sterile |
| Production | Microbial. Expressed in E. coli |
| Molecular Weight | 23 kDa (monomer) |
| Storage | Store lyophilized protein between -20 °C and -80 °C until the date of expiry. Avoid freeze-thaw cycles |
| Mycoplasma | Negative |
| Bioactivity Assay | No significant difference between EC50 of reference and test lots |
| Reconstitution | Resuspend in sterile-filtered water at >50 µg/ml. Once reconstituted, store in single-use aliquots to avoid freeze-thaw cycles. Store reconstituted protein at -20 °C to -80 °C for a maximum of 12 months or until the expiry date if sooner. |
| Shelf Life | This product has a guaranteed shelf-life of one year from the date of customer receipt when stored as recommended. |